'Greatest Hits' is a posthumous greatest hits album by the American rapper. The album's non-chronological sequence focuses on the highlights of the rappers career. The album is comprised of 21 tracks, accompanied by four previously unreleased songs. Features the singles 'Changes' and 'Unconditional Love'.

Tracklist:
Disc 1
1. Keep Ya Head Up (Feat. Dave Hollister)
2. 2 of Amerikaz Most Wanted - 2Pac & Snoop Dogg
3. Temptations
4. God Bless the Dead (Feat. Stretch)
5. Hail Mary (Feat. The Outlawz & Prince Ital Joe) - Makaveli
6. Me Against the World (Feat. Dramacydal and Puff Johnson)

Disc 2
1. How Do U Want It (Feat. K-Ci & JoJo)
2. So Many Tears
3. Unconditional Love (Feat. Nanci Fletcher)
4. Trapped (Feat. Shock G)
5. Life Goes On
6. Hit 'Em Up (Feat. Outlawz)

Disc 3
1. Troublesome 96'
2. Brenda's Got a Baby (Feat. Dave Hollister & Roniece)
3. I Ain't Mad at Cha (Feat. Danny Boy)
4. I Get Around (Feat. Digital Underground)
5. Changes (Feat. Talent)
6. California Love (Feat. Dr. Dre & Roger Troutman)
7. Picture Me Rollin' (Feat. Danny Boy, CPO & Big Syke)

Disc 4
1. How Long Will They Mourn Me? (Feat. Nate Dogg) - 2Pac, Rated R, Big Syke & Macadoshis
2. Toss It Up (Feat. Danny Boy, K-Ci & JoJo & Aaron Hall) - Makaveli
3. Dear Mama
4. All Bout U (Feat. Nate Dogg, Snoop Doggy Dogg, Hussein Fatal, Yaki Kadafi & Dru Down) [posthumous Remix]
5. To Live & Die in L.A. (Feat. Val Young) - Makaveli
6. Heartz of Men